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These effects are likely partly due to local increases in extracellular glutamate causing excitotoxicity, and reduced trophic support [e.g., platelet-derived growth factor (PDGF)] from astrocytes (Tognatta et al., 2020)
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Developed for advanced laboratory research, MT-2 is a potent, non-selective melanocortin receptor agonist (targeting MC1R, MC3R, MC4R, and MC5R)
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